Queen of Mean Lisa Lampanelli reveals how she lost 80 pounds with gastric sleeve surgery. Find out how her weight influenced her career and why she turned to food for comfort. Plus, Dr. Oz demonstrates how gastric sleeve surgery works.

View Part 1 of How Lisa Lampanelli Lost 80 Pounds.


Learn more about bariatric surgery for weight-loss.

Watch a sneak peek of Lisa’s one-woman show about her struggles with food.

Is gastric surgery right for you? Get a glimpse of Lisa’s post-surgery diet to find out.

Q: I end up overeating because it makes me feel better and I never really get full. I'd like to lose weight but this makes it hard. Any suggestions?

A: Being persistently hungry can cause big trouble. So can overeating for comfort/pleasure. These two behaviors, say researchers from Baylor University's Children's Nutrition Research Center, are controlled deep within your brain by serotonin-producing neurons, but operate separately from each other — one in the hypothalamus, the other in the midbrain. They both can, however, end up fueling poor nutritional choices and obesity.

Eating for Hunger

When hunger is your motive for eating, the question is: "Does your body know when you've had enough?" Well, if you are overweight, obese or have diabetes you may develop leptin resistance and your "I am full" hormone, leptin, can't do its job. The hormone's signal to your hypothalamus is dampened, and you keep eating.

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